Colindrez made her off-Broadway debut in 2006, starring in Too Much Light Makes the Baby Go Blind. She appeared in several short films and regional theatre productions after that, and in 2011 she wrote and starred in the film Otis Under Sky. In 2013, she began playing Joan in the musical Fun Home off-Broadway. The show closed in early 2014, and after a cameo in the Academy Award winning film Birdman, Fun Home opened on Broadway in 2015, where it won five Tony Awards. She stars in the show alongside Tony nominees Beth Malone, Emily Skeggs, and Sydney Lucas, two time Tony winner Michael Cerveris, three time Tony nominee Judy Kuhn, and Joel Perez. Colindrez has also made guest appearances on several television series. She also does voice acting work, most notably for her role in the podcast, Alice Isn't Dead.
