Nolasco has been nominated three times for an ALMA Award, and once for a Teen Choice Award.
Nolasco's additional television and film credits include guest-starring roles on George Lopez, CSI: NY and The Benchwarmers. He also appeared on Mind of Mencia as a guest on Sunday, April 29, 2007. He also starred in the movie adaptation of the Transformers, released during the summer of 2007. Director Michael Bay offered him to return to the sequel Transformers: Revenge of the Fallen, but he declined due to scheduling conflicts. His most high-profile role was Prison Break. Nolasco also has a role in "Telenovela."
In November 2009, Nolasco made an appearance in Wisin & Yandel's music video "Imagínate" featuring T-Pain alongside Wilmer Valderrama. He plays a jealous mobster who murders Valderrama's character for sleeping with his girlfriend. He also appears in Calle 13's music video "La Perla".
In March 2010, Nolasco guest-starred in 3 episodes during the second season of Southland as Detective Rene Cordero.
From September 2010 to May 2011, he costarred in the NBC show Chase, a one-season show about US Marshalls that hunt down Fugitives. He starred in the short-lived ABC television series Work It which premiered on January 3, 2012.
Nolasco was a supporter of the presidential campaign of Barack Obama. For the second year in a row, Nolasco was the host of the Amaury Nolasco & Friends Golf Classic that took place in El Conquistador Hotel in Fajardo, Puerto Rico from June 10–11, 2011. The Amaury Nolasco & Friends Golf Classic is a Celebrity golf tournament, where all the profits go to Non-Profit Puerto Rican organizations. For the second season, the profits went to the University of Puerto Rico Pediatric Hospital and to the VAL Foundation (Vive Alegre Luchando) an organization who gives their funding to pediatric cancer patients.
