Annie Patterson was born in Lurgan, County Armagh, Ireland, and was related through her mother's family to Lord Macaulay. She made her debut performance in Dublin at age fifteen, studied at Alexandra College and the Royal Irish Academy of Music in Dublin (with Robert Prescott Stewart), and received her doctorate in 1889, becoming the first British woman to hold a Doctorate of Music. After she completed her studies, she became an examiner for the Royal University of Ireland and worked as an organist and Conductor of the Dublin Choral Union and the Hampstead Harmonic Society. In 1897 she co-founded the Feis Ceoil festival in Dublin. The Dr. Annie Patterson Medal is awarded in her honor at the festival. In 1909 Patterson took a job as organist at St. Anne’s in Shandon, County Cork.