Garrick was featured in the 1993 movie Sleepless in Seattle.
She played DeDe Halcyon Day in the three television miniseries based on Armistead Maupin's Tales of the City novels. She was nominated for a Gemini Award in 1999 for Further Tales of the City.
She performed on several New York-based television shows, including several stints on soap operas. She portrayed the villainous nurse Charlotte Wheaton on Guiding Light in 1985, and on As the World Turns in 1999. She had several stints as cult follower Allison Perkins on One Life to Live, and first appeared as the character in 1986–1987, with subsequent stints in 2001–2002, 2003 and 2008. Garrick returned to the show in its final few months and was a prominent part of its final episode on January 13, 2012. Her character Allison narrated the entire episode and spoke the show's final words, "Things are rarely what they appear."
