On October 9, 1955, McGuire starred in the episode "Number Seven, Hangman's Row" of the CBS anthology series, Appointment with Adventure. He also starred in the Alfred Hitchcock Presents episodes "The Gentleman From America" (1956), "The Hidden Thing" (1956), "Crackpot" (1957), and "Don't Interrupt" (1958). He appeared in such television series as The Secret Storm, All My Children, and Gibbsville.
In a career that has spanned 50 years, McGuire has collected a number of theatrical credits. He was acclaimed for his role as Woody in the 1960 revival of the musical Finian's Rainbow and played King Arthur in one of the first national tours of Camelot. He was nominated for two Tony Awards during his career.
