Chambers became best known to soap fans as Maria Torres on the NBC soap opera Sunset Beach from 1998 to 1999.
In 2001 Chambers was cast on MTV's first and only soap opera Spyder Games. She played the role of the devious Taylor Jones, who ended being the killer in the murder mystery that carried the show from start to end.
In summer 2004, Chambers was the recast after Lesli Kay left the role of Molly Conlan on As the World Turns. She departed soon after her storyline ended. Also, in 2004, she portrayed Actress Jaclyn Smith in Behind the Camera: The Unauthorized Story of Charlie's Angels.
In November 2006, took over the role of Marty Saybrooke (previously played by Susan Haskell) on One Life to Live. In September 2007, it was announced that Chambers was let go from OLTL after only a year with the soap; she last aired December 4, 2007. Marty's original portrayer, Haskell returned in June 2008.
