Marzano appeared as a bilingual prostitute in Seven Psychopaths (2012), winning as part of Best Ensemble Cast at the 2012 Boston Society of Film Critics Awards, and nominated in the same category at the 2012 San Diego Film Critics Society Awards. She also had a supporting role as a brothel madam in the 2013 vampire film Byzantium and appeared in the 2013 thriller Paranoia. She portrayed Celebrity florist and landscape designer Charlotte Heavey in the 2015 film Dare to Be Wild and appeared in the 2016 Harry Potter prequel Fantastic Beasts and Where to Find Them, written by JK Rowling and directed by David Yates.