Rohner was born in Palo Alto, California. He is known for his role as Rick Morehouse in the 1985 comedy movie Just One of the Guys. He also starred in the 1986 film Modern Girls as Clifford and Bruno X. He is a main character in the 1994 film Caroline at Midnight. Other credits include the films April Fool's Day, Destroyer, The Relic, and The Human Centipede 3 (Final Sequence). Clayton starred in the short-lived science fiction series E.A.R.T.H. Force and G vs E. He starred in the 2005 film role in Formosa.
Rohner starred on the TV series Murder One as Detective Vince Biggio from 1996 to 1997. His television guest appearances include Miami Vice, Star Trek: The Next Generation as Admiral Mark Jameson in the season 1 episode "Too Short a Season", Beverly Hills, 90210, Charmed, Crossing Jordan, Angel, and Weeds. He also appeared in the award-winning series Into the West and The X-Files (season 6, episode 8). He also appeared in the TV role of Jared Pryor in the short-lived ABC midseason replacement Day Break.
