Vespoli started working as a stripper in 1996 using the stage name "Christa" at the Mitchell Brothers in San Francisco. She entered the adult film industry in 2003. Her first scene was in Ed Powers’ Dirty Debutantes series.
Vespoli married pornographic actor Manuel Ferrara in January 2005. The couple divorced seven years later. They have three sons together.
Vespoli started directing in January 2006. In April of that year, she began directing for Digital Sin. She currently directs for Sweetheart Video and Evil Angel. In 2011, Complex ranked her thirteenth on their list of "The Top 50 Hottest Asian Porn Stars of All Time". In 2014, Break.com ranked her 31st on their list of "40 Best Asian Porn Stars Today". Vespoli was inducted into the AVN Hall of Fame in 2016.
