From 1994 onwards, Brocklebank has starred in various TV programmes such as Down to Earth (BBC), Born and Bred (BBC), Ed Stone is Dead (BBC 3/Channel 4), Casualty (BBC), The Bill (ITV) and played Ivan Jones in ITV's Emmerdale between the beginning of 2005 to the end of 2006. Other TV credits include: The Crazy World of Captain Llama, Fair City, Doctors and Waterloo Road.
Amongst other projects in 2008, Brocklebank starred in One Night In November, a new play by Alan Pollock directed by Hamish Glenn at the Belgrade Theatre, and in Big Love at the Abbey Theatre, Dublin, directed by Selina Cartmell.
In 2009, Brocklebank played Brother Jasper and Kaisa in His Dark Materials, a co-production between the Birmingham Rep and the West Yorkshire Playhouse directed by Rachel Kavanaugh and Sarah Esdaile. In 2009 Brocklebank completed filming Release, a British feature film, written by Christian Martin and Darren Flaxstone of FAQ's LTD in which he plays the lead role of Father Jack Gillie.
In 2010, Brocklebank starred in one of three new dark tales Little Deaths directed by Andrew Parkinson, whose previous projects include I, Zombie, Dead Creatures and Venus Drowning. He also completed Age Of Heroes, in which he plays Sergeant Hamilton, a small role, opposite Danny Dyer and Sean Bean.
In December 2014, Brocklebank joined the cast of Coronation Street, as Billy Mayhew, the new vicar at Emily Bishop's parish, St. Mary's and began dating barman Sean Tully. He also appears as Carl Saunders in the second (2014) and third (2015) series of the BBC's WPC 56 involved with Inspector Briggs, "Admiral" a movie where Daniel plays opposite Charles Dance, "Soft Lad" a movie written and directed by Leon Lopez and "Native" and Sci-Fi movie playing opposite Rupert Graves. Ellie Kendrick
In 2017, Brocklebank entered into a relationship with his Coronation Street co-star Rob Mallard, who plays Daniel Osbourne. The couple later split up but remain good friends. In late 2017, Brocklebank announced via social media he was dating former Mr. Gay Europe Stuart Hatton Jr.
