Fluegel started her modeling career in 1974 and ended it in 1981. She made her screen debut with a supporting role in the 1978 film Eyes of Laura Mars. Her first major film role was as Nanelia in the cult sci-fi film Battle Beyond the Stars (1980). She was featured in Sergio Leone's film Once Upon a Time in America (1984) as Robert De Niro's girlfriend Eve, and in Tough Guys (1986) as Kirk Douglas' girlfriend. In 1985, she appeared in To Live and Die in L.A. as Ruth Lanier, the love interest of william Petersen's main character, Secret Service Agent Richard Chance. Not long afterward, in 1986, she portrayed Billy Crystal's ex-wife, Anna, in the buddy-cop action comedy Running Scared. As a lead Actress, Fluegel starred in the independent film Freeway (1988).