Other notable stage performances include Riddley Walker, Oedipus, Macbeth, Your Home In The West and Peer Gynt at the Royal Exchange Theatre, Manchester, Bolingbroke in Richard II and Orgon in Tartuffe at the National Theatre in London. Threlfall played Jack in When the Whales Came (1989), opposite Paul Scofield and Helen Mirren. In 2010, he appeared as a guest on Have I Got News for You.