Following Campbell's death in 1781, she married Gen. william Russell in 1783. They lived at Aspenvale, Virginia until 1788 when they moved to Saltville, Virginia where they carried on the manufacture of salt. The Russells converted to Methodism in 1788. After Gen. Russell's death in 1793, Elizabeth spent the remainder of her life fostering Methodism in southwestern Virginia and northeastern Tennessee. Francis Asbury and various Circuit Riders stopped regularly at her home. She is credited with bringing Methodism to western Virginia and northeastern Tennessee. In 1812 she moved to Chilhowie, Virginia to be nearer the Great Road. She died in March 1825 and is buried in the Aspenvale Cemetery.