In 2008, Ambani, with a net worth of ₹4,710 crore (US$720 million), was ranked 2nd on the Forbes' Youngest Billionaire Heiresses list, and in 2015 was named among 12 powerful upcoming Business Women in Asia.
In 2014, after receiving an undergraduate degree in Psychology and South Asian studies from Yale University, Ambani worked as a Business analyst with the management consulting firm, McKinsey & Company. Later that year, she was inducted into the boards of Directors of Reliance Jio and Reliance Retail.
In December 2015, she led the employee launch of Jio's 4G services along with her brother in the presence of the brand's ambassador, Shah Rukh Khan.
In April 2016, Ambani launched AJIO, an online fashion retailer, at the 2016 edition of Lakme Fashion Week. She oversees the branding and management segments of AJIO, which is a subsidiary of Reliance Retail.
