Zagorsky's most notable role was Dr. Julia Walker in Helix. She had guest star appearances in SyFy's Continuum (TV series) in its final season, as well as Stargate: Atlantis and Stargate Universe SGU, The CW's Supernatural, FOX's Fringe, TNT's Falling Skies and in the award winning web series Divine. Zagorsky took on a lead role in the film The ABCs of Death, "a 26-chapter anthology that showcases death in all its vicious wonder and brutal beauty", which premiered at the 2012 Toronto International Film Festival and in the zombie horror film Toxin 3D.