In 2010, he was diagnosed with cancer; he died on February 13, 2011 after a long illness. He was 49 years old. His wife, Hanne Kristiansen, died in July 2015. He is survived by his mother, Friederike; his brother, Dr. Patrick Holden, and his wife, Beth; his sisters, Angela Holden and Deborah Holden-Baker; and four nephews and one niece.