Laura's first film appearance was in the 1992 movie The Public Eye, starring Joe Pesci. This was followed by a small part in the 1995 movie Losing Isaiah. After playing the recurring role of Anita Marrón on the short-lived 1993–1994 ABC drama Missing Persons, Laura joined the supporting cast of the NBC drama ER in 1995, near the end of its first season. Laura was one of only six actors to appear in every season of ER until the final episode in April 2009. She guest starred in Strong Medicine in 2004. In 2009, she starred in the fifth installment of Bring It On, alongside singer/actress Christina Milian.