Sanchez became engaged to actor Henry Simmons (NYPD Blue), but split with him in 2003. In August 2005, she married Patrick Whitesell, a Hollywood agent who represents acting talents like Matt Damon, Hugh Jackman, and Ben Affleck. The wedding was a star-studded affair with a price tag of two million dollars. Sánchez has two sons and one daughter: Nikko, born 2001, from a previous relationship with former NFL tight end Tony Gonzalez; Evan, born 2006; and Ella, born in 2008.