In July 2016, Alexander presented the first episode of the 5-part BBC documentary series Matron, Medicine and Me: 70 Years of the NHS in which she explored the current and historical medical treatment of patients with disabilities in the UK and described her own family's experience of the National Health Service after her daughter was diagnosed with transverse myelitis. In 2017, she appeared in Channel 4's Tried and Tasted: The Ultimate Shopping List. She began presenting the daytime Channel 4 series Best of Both Worlds in 2017, replacing Kirstie Allsopp. In 2017 she co-presented Lost and Found on Channel 4 daytime with Simon O'Brien.