In the early 1990s, she began to collaborate with the notable French filmmaker Gaspar Noé. She edited his short film Carne (1991) and its sequel, the feature length I Stand Alone (1998), and together they formed the production company Les Cinémas de la Zone in 1991. Noe explained their coming together as Business partners: "we discovered that we shared a Desire to make films atypical and we decided together to create our own society, Les Cinémas de la Zone, in order to Finance our projects." Hadžihalilović’s first film after her graduation, La Bouche de Jean-Pierre (1996), was a result of this collaborative effort. Hadžihalilović wrote, edited, produced, and directed the film while Noé worked as the Cinematographer. La Bouche de Jean-Pierre was shown during the Un Certain Regard panel at the Cannes Film Festival as well as being selected for various other notable festivals throughout the world. Hadžihalilović also contributed to the screenplay of Noe's critically divisive Enter the Void (2009).