Mancuso was born May 29, 1948 in Mammola, Calabria, Italy and emigrated to Canada in 1956.
In the early 1980s, Mancuso starred in Ticket to Heaven in which he played the part of a David Kappel, a non-observant Jewish Teacher in Toronto. His girlfriend leaves him and he visits San Francisco to find his footing and see an old friend. He is lured into spending a weekend at a camp that is actually the recruiting and indoctrination center for a religious cult. It becomes apparent that this film is based on the Unification Church.
Mancuso's first marriage took place in Los Angeles, Los Angeles County, California, on 24/26 May 1981 to Lady Patricia Pelham-Clinton-Hope (born Salisbury, Southern Rhodesia, 20 July 1949), daughter of the 9th Duke of Newcastle-under-Lyne, film Actress on two occasions, on Mask (1985) as Canuck's Girl and on Tales from the DarkSide, episode "A New Lease on Life" (1986) as Helen Tanner. She was a former wife of Alan Parker, whom she married on 1 December 1971 and divorced in 1974. They divorced in 1983, when she reverted to her maiden name, and had no children.
In 1998 Mancuso married his third wife, Actress Nadia Capone, whom he divorced in 2006. His only child is a result of that union.
