Assayas was born in Paris, France, the son of French director/screenwriter Raymond Assayas, alias Jacques Rémy (1911–1981). His father was of Turkish Jewish and Greek Jewish origin who had settled in Italy, whereas his mother was of Protestant Hungarian origin. Assayas started his career in the industry by helping his father. He ghostwrote episodes for TV shows his father was working on when his health failed. In a 2010 interview, Assayas stated that his main political influences when growing up were Guy Debord and George Orwell. Speaking of the 1968 May uprising to overthrow General de Gaulle, Assayas in the same interview stated: "I was defined by the politics of May '68, but for me May '68 was an anti-totalitarian uprising. People seemed to forget that at the occupied Odéon theater, you had crossed flags-black and red, and I was on the side of the black element.".