Edwards was born in Oklahoma City, Oklahoma. She acted professionally from 1963 and is best known for the role of the domineering Corabeth Walton Godsey, the wife of storekeeper Ike Godsey played by Joe Conley, in the CBS television series The Waltons, created by Earl Hamner, Jr. She played Charlene's mother Ione Frazier on two episodes of CBS's Designing Women. Edwards played Aunt Dolly in Hamner's series Boone, which aired on NBC from 1983 to 1984. She co-starred in the NBC series Sara (1985) opposite Geena Davis. She briefly appeared on an episode of PBS's Antiques Roadshow (2008) from Dallas, Texas, when she brought in for appraisal a chair formerly owned by P.T. Barnum. She also appeared in the Star Trek: The Next Generation episode "Thine Own Self" and the remake of Inherit the Wind (1999).