At 16, Parkes enrolled at Seltec College to study drama. Two years later, he was accepted into RADA. Having acted in both theatre and television support roles, Parkes made his breakthrough in the 1999 film Human Traffic. His work since then includes films such as Clubbed, The Mummy Returns, Things to Do Before You're 30 and the acclaimed Notes on a Scandal. Television work includes Lock, Stock..., Servants and Russell T Davies' Casanova and Doctor Who.