While simultaneously appearing on Cheers, she continued starring in several motion pictures. In 1984, she was nominated for a Best Leading Actress Golden Globe for her performance in Irreconcilable Differences. She then starred in a series of comedies, such as The Money Pit, with Tom Hanks, Outrageous Fortune, with Bette Midler and Peter Coyote, and Hello Again, with Corbin Bernsen. She was also offered lead roles in Working Girl, Jumpin' Jack Flash and My Stepmother Is an Alien, but did not accept those roles.