Peake-Jones is best known for playing Raquel Turner, the longtime partner of the main character Derek "Del Boy" Trotter, in the television comedy Only Fools and Horses. She had a co-starring role in the 1999 TV series Births, Marriages, and Deaths. Her other television appearances include The Demon Headmaster, Midsomer Murders, Casualty, Holby City, The Bill, Up the Garden Path and So Haunt Me.