When Parker became pregnant, Amy was written out of the show in the fifth season episode "Constituency of One". After coming into conflict with President Bartlet over funding for domestic violence prevention in an Appropriations bill for the Department of Health and Human Services, she realizes that her methods do not suit a position at the White House—she prefers to pursue her own agenda instead of furthering someone else's political career. She resigns as Chief of Staff to the First Lady and ends her relationship with Josh again.