The Bradstreet family soon moved again, this time to what is now Cambridge, Massachusetts. In 1632, Anne had her first child, Samuel, in Newe Towne, as it was then called. Despite poor health, she had eight children and achieved a comfortable social standing. Having previously been afflicted with smallpox as a teenager in England, Anne would once again fall prey to illness as paralysis overtook her joints in later years. In the early 1640s, Simon once again pressed his wife, pregnant with her sixth child, to move for the sixth time, from Ipswich, Massachusetts to Andover Parish. North Andover is that original town founded in 1646 by the Stevens, Osgood, Johnson, Farnum, Barker, and Bradstreet families among others. Anne and her family resided in the Old Center of North Andover, Massachusetts [1]. They never lived in what is now known as "Andover" to the south.