Moriarty voiced characters in the animated TV series Stories from My Childhood episodes "The Golden Rooster" and "The Wild Swans" and the animated series Recess episode "Kids in the Mist". Other appearances included Hilary Duff's witch aunt in the direct-to-video film, Casper Meets Wendy; Randy Quaid's wife in the direct-to-video film, P.U.N.K.S., and Sharon Stone's friend in Gloria (a 1999 remake of the 1980 film written and directed by John Cassavetes). Roles followed in Crazy in Alabama, a film adaptation of Mark Childress's 1993 novel of the same name; New Waterford Girl, a Canadian comedy-drama, and the satirical film But I'm a Cheerleader. Moriarty played an FBI agent in Red Team, an abusive adoptive mother in the family film Prince of Central Park and a woman who fears death in the short film Next Stop, Eternity. Other roles included a widow suspected of killing her husband in an episode of Law & Order, crime boss Patti LoPresti in the Mafia comedy film (and sequel to 1999's Analyze This) Analyze That and a controlling mother in an episode of Law & Order: Special Victims Unit. In 2010, Moriarty played a bookie who sends two thugs to kill the main characters (Jennifer Aniston and Gerard Butler) in the romantic-action-comedy film The Bounty Hunter. On July 18, 2010, the Long Island International Film Expo honored the Actress with its Long Island Creative Achievement Award. Shortly afterwards, she guest-starred as Annalisa Gentili on an episode of Law & Order: Criminal Intent. The next year, Moriarty appeared as a nurse in the film 1320. In 2013 she played Armand Assante's wife in Once Upon a Time in Brooklyn and a sarcastic waitress in a black comedy, The Double. She returned to Law & Order: Special Victims Unit as Lieutenant Toni Howard for two episodes: season 14's "Poisoned Motive" and season 15's "Amaro's One-Eighty".