Taylor, as many Australian actors, got her big breakthrough in the Australian soap opera Neighbours in 2005. She secured the role of Janae Timmins after previously appearing in a guest role in 2003. Taylor had originally auditioned for the role of Lana Crawford, however, it was Actress Bridget Neval who was eventually cast. In 2007, Nell Feeney and Sianoa Smit-McPhee, who play Taylor's on-screen mother Janelle Timmins and sister Bree Timmins, were written out by executive Producer Ric Pellizzeri, but it was confirmed that they wanted Taylor-Cotter to remain in the serial as Janae. Later that year, Taylor-Cotter decided to quit the serial to pursue other projects such as pantomime and a further career in the USA. One of the contributing factors that helped Taylor-Cotter reach this decision was that all of her on-screen family had been written out and new cast members gave the serial the feel of a different place. She also added: "It just didn't feel like the family that I joined when I started three years ago. Taylor-Cotter was one of many cast members that quit the serial at the same time. Taylor-Cotter finished filming her final studio scenes in 2007 and her final episode was screened on 8 February 2008. In 2007, Taylor was nominated for Best Female at the Inside Soap Awards.