Originally from Buffalo, New York, she is most famous for her role of Geri Tyler on the television program The Facts of Life from 1980 to 1984. This role made her the first person with a visible disability to have a regular role on a prime time series, as well as the first actor with cerebral palsy to be featured on a TV series. After she dropped out of college, Jewell's began her career doing stand up comedy at The Comedy Store in 1978. In 1980, she performed at the 2nd Annual Media Access Awards, when she was introduced to Norman Lear by Producer, Fern Field.