Gloria Blondell said that she first went on stage when she was 9 months old, and she was described as "a trouper at three [years of age]." Her family comprised a vaudeville troupe, the "Bouncing Blondells", whose members were her parents, her sister and her brother. In 1935, she appeared in the Broadway production of Three Men on a Horse at the Playhouse in New York City.
Blondell co-starred with Ronald Reagan in Accidents Will Happen (1938) and with Hans Conried in The Twonky (1953). She was also in Daredevil Drivers (1938) and Three Sappy People (1939)
She married film Producer Albert Broccoli on July 26, 1940; they divorced August 7, 1945. On September 14, 1946, she married Victor Hunter in Monterey, California. They remained married until his death in 1980, just weeks after her sister's death.
She died at age 75 in 1986 in Santa Monica, California from cancer and was interred in Forest Lawn Memorial Park Cemetery, Glendale, California.
