Fisher is best known for his portrayal of his character Rab C. Nesbitt in the sitcom of the same name, this itself was a spin-off from the BBC2 Sketch comedy Naked Video, where the Nesbitt character originated, along with The Baldy Man who also obtained his own eponymous spin-off series, and is particularly associated with two Hamlet adverts involving photography, the first of which where he cannot get a satisfactory passport photo from a photobooth and Lights up a cigar to calm himself down; the second of which where he cannot get a satisfactory family portrait and Lights up a cigar to calm himself down. Johnny Depp based his Glaswegian accent for the role of Tarrant Hightopp, The Mad Hatter in the 2010 film Alice in Wonderland, on that used by Fisher’s Rab C. Nesbitt character.