Suttie trained as an Actress at the Guildford School of Acting, graduating in 2000. In 2001 she composed and directed a score for Peter Weiss' play Marat/Sade at the Arcola Theatre in London. Suttie began performing stand-up comedy in 2003. Her act normally consists of music, stand-up and stories, either as herself or under the guise of a character.
At the 2005 Edinburgh Fringe, Suttie was one of the acts in stand-up showcase The Comedy Zone. In 2006, she acted in Danielle Ward's Take-a-Break Tales at The Pleasance with Neil Edmond and Emma Fryer. In 2007, she performed her debut solo stand-up show, Love Lost in the British Retail Industry, which she took to Sydney Arts Festival and on a UK tour in 2010–11, and in 2008 her second solo Edinburgh show The Suttie Show. She played psycho killer Sorrow in the revival of Danielle Ward and Martin White's cult musical Gutted at the Leicester Square Theatre for two performances in February and March 2011. She took her third solo stand-up show, Pearl and Dave, to Edinburgh in August 2011. She appeared at the Just for Laughs Comedy Festival in Montreal in July 2012.
She was cast as IT geek Dobby in Peep Show in 2008, a role that she continued to play for the remainder of the show's run until 2015.
Suttie played a waitress called Kiki alongside Alan Davies in BBC Two's Whites, which aired in autumn 2010. She has also made TV appearances in Holby City, as Mary Shelley in The Trouble With Love (BBC Two), as various characters in The Incredible Will and Greg (Channel 4), as Lianne in Rab C. Nesbitt (BBC), as a judge in Genie in the House and as a nurse in two episodes of Skins (Channel 4).
In 2012, Suttie voice-acted in the CBBC show The Cow that Almost Missed Christmas alongside Johnny Vegas. The show was a one-off animation which gave a unique interpretation of the Christmas Nativity seen through the eyes of a cow called Marjorie, who Suttie voiced.
In August 2013, Suttie appeared in the one-off revival episode of the television series Knightmare as Treguard's assistant Veruca/Daisy. The 26-minute episode was aired as part of YouTube's "Geek Week" celebrations.
Suttie is engaged to Welsh Comedian Elis James. The couple live in London and have one daughter, born October 2014.
In September 2016, she began a six-episode run on the Channel 4 TV show Damned as Natalie, a temporary receptionist. She also appeared in the sitcom Man Down as Miss Clarke.
