Morgridge was born to L. D. Morgridge and Ruth Gordon Morgridge, who were both teachers and church members. He has one brother, Dean L. Morgridge, and one sister, Barbara Morgridge. He grew up in Wauwatosa, Wisconsin, where he attended Wauwatosa East High School. He worked part-time at jobs such as washing equipment in a sweet pea cannery, digging stone at the quarry in Lannon, washing walls in Milwaukee's Pabst Brewery, doing road construction on Highway 64, and working as a railroad brakeman. In 1955, he graduated from the University of Wisconsin and in 1957, he earned a MBA from Stanford University.