Anderson-Lopez was raised in Croton-on-Hudson, New York (a suburb of New York City), until 1986; the Myers Park neighborhood of Charlotte, North Carolina, from 1986 to 1990; and Waxhaw, North Carolina (a suburb of Charlotte), from 1990 onward (which was her home during her college years). Her parents, Erin and John, still live in Waxhaw. According to her father, Anderson-Lopez first fell in love with the theater at the age of four, when he took her to see a U.S. Bicentennial musical tribute staged in their then-hometown of Croton-on-Hudson. After her family moved to North Carolina, she attended and graduated from Charlotte Country Day School. She went on to Williams College in western Massachusetts, where she double-majored in drama and psychology and graduated in 1994. After a theater internship in Florida, Anderson-Lopez spent several years working temporary jobs while pursuing her dream of becoming a Broadway theatre performer in New York City. In 1999, she entered the BMI Lehman Engel Musical Theatre Workshop and found her true calling as a lyricist, and also met her Future husband Robert Lopez.