Three weeks later, on December 18, 1869, at the age of 40, he died at his hotel in Tijuca, Rio de Janeiro, probably from an overdose of quinine. (According to an essay by Jeremy Nicholas for the booklet accompanying the recording "Gottschalk Piano Music" performed by Philip Martin on the Hyperion label, "He died ... of empyema, the result of a ruptured abscess in the abdomen.")