Sudeep began his film career in Thayavva (1997). He then played a supporting role in Prathyartha, directed by Sunil Kumar Desai, and a lead role in the same director's Sparsha (film)|Sparsha. In 2001, a role in Huchcha gave him his first big following. In 2008 he made his Bollywood debut in Phoonk. He has also starred in Ram Gopal Varma's movies Rann, Phoonk 2 and Rakta Charitra. They were followed by Kempe Gowda and Vishnuvardhana (2011).
Sudeep met Priya Radhakrishnan, belonging to the Nair community of Kerala, in Bangalore, in 2000 and they married in 2001. Priya worked in an airline company and then in a bank, prior to their marriage. Their only child, Saanvi, was born in 2004. In 2013, Sudeep launched Stage 360°, an events management company, that his wife took an active part in. The couple split in September 2015, and reconciled
He frequently sings in his screen roles, including Vaalee (2001), Chandu (2002), Ranga SSLC (2004), Nalla (2004), #73, Shaanthi Nivaasa (2007), Veera Madakari (2009), Kempe Gowda]] (2011), Bachchan (2013) and also for others movies such as Mandya to Mumbai (2014), Ring Road Shubha (2014), Raate(2015).
He owns a film production company named Kiccha Creations which is credited with My Autograph (2006) and No 73, Shanthi Nivasa (2007).
In 2012, Sudeep was signed as the Brand Ambassador of Joy Alukkas, a Jewellery Retail Chain. In 2013, he was appointed as the Brand Ambassador for Bangalore Traffic Police Department and Income Tax Department. In 2014, he was appointed as the Brand Ambassador for Intex Technologies (India) Mobiles & Paragon Footwear.
In 2013, on World AIDS Day, Sudeep teamed up with Vijay Raghavendra and other actors to record voiceovers for the TeachAIDS interactive software, developed at Stanford University.
In 2015, Sudeep appeared in advertisements in the Kannada language for OLX.in, along with the veteran Kannada actor, Anant Nag. He had previously appeared in ads with Sadhu Kokila for the same company.
