Sarandos married Michelle Sarandos, his first wife, with whom he had two children, Sarah and Tony. In 2009, Sarandos married former United States Ambassador to the Bahamas (2009-2011), Nicole Avant, the daughter of former Motown Chairman Clarence Avant. Producer Lawrence Bender introduced Sarandos to Avant. The couple live in the Hancock Park neighborhood of Los Angeles, after previously living in Avant's home town of Beverly Hills, California. In 2013, the couple purchased a beach house formerly owned by David Spade in Malibu, California. Sarandos has said he is Catholic.